Impact of histone modifier-induced protection against autoimmune encephalomyelitis on multiple sclerosis treatment
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DOI: 10.3389/fneur.2022.980758
Abstract: Multiple sclerosis is a progressive demyelinating central nervous system disorder with unknown etiology. The condition has heterogeneous presentations, including relapsing-remitting multiple sclerosis and secondary and primary progressive multiple sclerosis. The genetic and epigenetic mechanisms underlying… read more here.
Keywords: multiple sclerosis; impact histone; sclerosis; disease modifying ... See more keywords
Impact of Histone Modifications and Their Therapeutic Targeting in Hematological Malignancies
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DOI: 10.3390/ijms232113657
Abstract: Hematologic malignancies are a large and heterogeneous group of neoplasms characterized by complex pathogenetic mechanisms. The abnormal regulation of epigenetic mechanisms and specifically, histone modifications, has been demonstrated to play a central role in hematological… read more here.
Keywords: histone modifications; impact histone; targeting hematological; modifications therapeutic ... See more keywords