Articles with "impact hotspot" as a keyword



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Abstract 4754: Investigating the impact of hotspot mutations in a chromatin reader on leukemogenesis

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-4754

Abstract: Acute myeloid leukemia (AML) is one of the most aggressive forms of hematological malignancies with a low overall 5-year survival rate (< 26%). The mainstay of treatment for AML includes chemotherapy, but the response of… read more here.

Keywords: chromatin reader; hotspot mutations; investigating impact; mutations chromatin ... See more keywords