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Published in 2018 at "Biochimie"
DOI: 10.1016/j.biochi.2018.07.008
Abstract: In recent years, we have witnessed a significant increase in the amount of studies using Mesenchymal Stem Cells (MSCs) for cancer therapy, mostly as vectors for drug or gene delivery strategies. This is because of…
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Keywords:
impact mesenchymal;
treatment;
cancer;
stem cells ... See more keywords
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Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007528
Abstract: Key Points • The PLEKHM1-associated endolysosomal system in MSCs affects BCR-ABL1+ B-ALL progression via release of extracellular vesicles.• B-ALL–derived inflammatory cytokines perpetuate this circuit in MSCs, modify vesicular cargo, and promote B-ALL cell signaling and…
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Keywords:
cell;
mesenchymal stromal;
progression;
impact mesenchymal ... See more keywords