Psychiatric drugs impact mitochondrial function in brain and other tissues
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Research"
DOI: 10.1016/j.schres.2019.09.007
Abstract: Mitochondria have been linked to the etiology of schizophrenia (SZ). However, studies of mitochondria in SZ might be confounded by the effects of pharmacological treatment with antipsychotic drugs (APDs) and other common medications. This review… read more here.
Keywords: psychiatric drugs; drugs impact; treatment; mitochondria ... See more keywords
Impact of Mitochondrial Targeting Antibiotics on Mitochondrial Function and Proliferation of Cancer Cells.
Sign Up to like & getrecommendations! Published in 2021 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.0c00632
Abstract: Some marketed antibiotics can cause mitochondria dysfunction via inhibition of the mitochondrial translation process. There is great interest in exploiting such effects within a cancer setting. To enhance accumulation of antibiotics within the mitochondria of… read more here.
Keywords: antibiotics mitochondrial; targeting antibiotics; mitochondrial targeting; cancer cells ... See more keywords
Changes in PGC‐1α/SIRT1 Signaling Impact on Mitochondrial Homeostasis in Amyloid-Beta Peptide Toxicity Model
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.00709
Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive impairment that increasingly afflicts the elderly population. Soluble oligomers (AβOs) has been implicated in AD pathogenesis: however, the molecular events underlying a role for Aβ… read more here.
Keywords: changes pgc; sirt1 signaling; pgc sirt1; signaling impact ... See more keywords
A Systematic Review of the Impact of Mitochondrial Variations on Male Infertility
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13071182
Abstract: According to current estimates, infertility affects one in four couples trying to conceive. Primary or secondary infertility can be due either to both partners or only to the man or the woman. Up to 15%… read more here.
Keywords: review impact; systematic review; infertility; impact mitochondrial ... See more keywords