Articles with "impact oncogenic" as a keyword



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Impact of oncogenic pathways on evasion of antitumour immune responses

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Published in 2018 at "Nature Reviews Cancer"

DOI: 10.1038/nrc.2017.117

Abstract: Immunotherapeutic interventions are showing effectiveness across a wide range of cancer types, but only a subset of patients shows clinical response to therapy. Responsiveness to checkpoint blockade immunotherapy is favoured by the presence of a… read more here.

Keywords: pathways evasion; immune responses; evasion antitumour; impact oncogenic ... See more keywords

Clinical impact of oncogenic KRASdosage variation in pancreatic cancer.

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Published in 2024 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2024.42.16_suppl.4027

Abstract: 4027 Background: Some studies have reported that KRAS oncogenic dosage variation plays a critical role in the biology and phenotype diversification of pancreatic ductal adenocarcinoma (PDA). However, this has not been confirmed in large-scale data.… read more here.

Keywords: clinical impact; variation; group; impact oncogenic ... See more keywords