The impact of proton pump inhibitors in liver diseases and the effects on the liver
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Digestive Diseases"
DOI: 10.1111/1751-2980.13093
Abstract: In this systematic and comprehensive overview, we aimed to evaluate the impact of proton pump inhibitors (PPIs) on chronic liver diseases, especially on cirrhosis. A manual and comprehensive search of the PubMed database was conducted… read more here.
Keywords: effects liver; pump inhibitors; proton pump; liver diseases ... See more keywords
Impact of proton pump inhibitors (PPIs) on sunitinib (SU) pharmacokinetics (PK) and activity in GIST patients (pts).
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.11538
Abstract: 11538Background: PPIs alter the PK of several oral drugs, either through a decrease in absorption due to higher GI tract pH, or the induction of efflux pumps such as ABCB1. The PK of SU is… read more here.
Keywords: pump inhibitors; inhibitors ppis; ppis sunitinib; sunitinib pharmacokinetics ... See more keywords
Quantifying the Dosimetric Impact of Proton Range Uncertainties on RBE-Weighted Dose Distributions in Intensity-Modulated Proton Therapy for Bilateral Head and Neck Cancer
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DOI: 10.3390/curroncol31070272
Abstract: Background: In current clinical practice, intensity-modulated proton therapy (IMPT) head and neck cancer (HNC) plans are generated using a constant relative biological effectiveness (cRBE) of 1.1. The primary goal of this study was to explore… read more here.
Keywords: proton; therapy; range uncertainties; impact proton ... See more keywords