Impact of the Recognition Part of Dipeptidyl Nitroalkene Compounds on the Inhibition Mechanism of Cysteine Proteases Cruzain and Cathepsin L
Sign Up to like & getrecommendations! Published in 2023 at "ACS Catalysis"
DOI: 10.1021/acscatal.3c01035
Abstract: Cysteine proteases (CPs) are an important class of enzymes, many of which are responsible for several human diseases. For instance, cruzain of protozoan parasite Trypanosoma cruzi is responsible for the Chagas disease, while the role… read more here.
Keywords: cysteine proteases; nitroalkene compounds; impact recognition; inhibition ... See more keywords
A pyrene-functionalized foldamer: structural impact and recognition properties supported by donor-acceptor interactions.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc07253h
Abstract: An electroactive and luminescent foldamer based on an oligopyridine biscarboxamide skeleton was synthesized and characterised. Its conformation in the solid state proved to be strongly affected by the peripheral pyrene units. The latter also endow… read more here.
Keywords: pyrene functionalized; recognition; functionalized foldamer; impact recognition ... See more keywords