Altering the central carbon metabolism of HEK293 cells: Impact on recombinant glycoprotein quality.
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DOI: 10.1016/j.jbiotec.2016.12.003
Abstract: The accumulation of metabolic by-products remains a critical challenge in the development of mammalian cells culture processes as it impacts cellular growth, productivity and product quality. Although the overexpression of the PYC2 gene was shown… read more here.
Keywords: impact recombinant; quality; metabolism; cells impact ... See more keywords