Impact of statins on cellular respiration and de‐differentiation of myofibroblasts in human failing hearts
Sign Up to like & getrecommendations! Published in 2019 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12509
Abstract: Fibroblast to myofibroblast trans‐differentiation with altered bioenergetics precedes cardiac fibrosis (CF). Either prevention of differentiation or promotion of de‐differentiation could mitigate CF‐related pathologies. We determined whether 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A (HMG‐CoA) reductase inhibitors—statins, commonly prescribed to patients… read more here.
Keywords: differentiation myofibroblasts; cellular respiration; impact statins; differentiation ... See more keywords
Impact of statins on outcomes in patients (pts) with metastatic castration resistant prostate cancer (mCRPC): Post-hoc analysis of data from COU-AA-301 and COU-AA-302 trials.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.6_suppl.230
Abstract: 230Background: Retrospective database studies have suggested that statins may have a positive impact on some mCRPC pts treated with prednisone (P)/abiraterone (AA) Methods: We conducted a post-hoc analysis of individual pt data of mCRPC pts… read more here.
Keywords: hoc analysis; post hoc; 301 cou; impact statins ... See more keywords
IMPACT OF STATINS ON THE CLINICAL COURSE OF COVID-19-ASSOCIATED PNEUMONIA IN UNVACCINATED PATIENTS WITH ARTERIAL HYPERTENSION.
Sign Up to like & getrecommendations! Published in 2023 at "Wiadomosci lekarskie"
DOI: 10.36740/wlek202302110
Abstract: OBJECTIVE The aim: To assess the impact of statins on the severity and lethality rate in hypertensive patients with COVID-19-associated pneumonia. PATIENTS AND METHODS Materials and methods: 106 unvaccinated hypertensive patients were enrolled in the… read more here.
Keywords: associated pneumonia; covid associated; impact statins; hypertensive patients ... See more keywords