Impact of target interactions on small-molecule drug disposition: an overlooked area
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DOI: 10.1038/nrd.2018.26
Abstract: The selection of an appropriate drug target, as well as a solid understanding of drug pharmacokinetics and pharmacodynamics, are crucial for successful drug discovery1. Although it is generally accepted that the free (unbound) concentration of… read more here.
Keywords: drug binding; molecule drug; small molecule; target ... See more keywords