Impaired dentin mineralization, supernumerary teeth, hypoplastic mandibular condyles with long condylar necks, and a TRPS1 mutation.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2020.104735
Abstract: Tricho-rhino-phalangeal syndrome type I, an autosomal dominant condition, is caused by heterozygous pathogenic variants in a zinc finger transcription factor, TRPS1, which has important roles in development of endochondral bones, teeth, and hair. Clinical manifestations… read more here.
Keywords: dentin mineralization; impaired dentin; supernumerary teeth; trps1 ... See more keywords