STIM1 R304W causes muscle degeneration and impaired platelet activation in mice.
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DOI: 10.1016/j.ceca.2018.10.001
Abstract: STIM1 and ORAI1 regulate store-operated Ca2+ entry (SOCE) in most cell types, and mutations in these proteins have deleterious and diverse effects. We established a mouse line expressing the STIM1 R304 W gain-of-function mutation causing Stormorken… read more here.
Keywords: stim1; platelet activation; muscle degeneration; impaired platelet ... See more keywords