Astrocyte dystrophy in ageing brain parallels impaired synaptic plasticity
Sign Up to like & getrecommendations! Published in 2021 at "Aging Cell"
DOI: 10.1111/acel.13334
Abstract: Little is known about age‐dependent changes in structure and function of astrocytes and of the impact of these on the cognitive decline in the senescent brain. The prevalent view on the age‐dependent increase in reactive… read more here.
Keywords: age dependent; ageing brain; dystrophy ageing; impaired synaptic ... See more keywords
Microglial transglutaminase 2 deficiency causes impaired synaptic remodelling and cognitive deficits in mice.
Sign Up to like & getrecommendations! Published in 2023 at "Cell proliferation"
DOI: 10.1111/cpr.13439
Abstract: Microglia are the primary source of transglutaminase 2 (TGM2) in the brain; however, the roles of microglial TGM2 in neural development and disease are still not well known. The aim of this study is to… read more here.
Keywords: impaired synaptic; cognitive deficits; deficits mice; causes impaired ... See more keywords