Thrombocytopathy leading to impaired in vivo haemostasis and thrombosis in platelet type von Willebrand disease.
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DOI: 10.1160/th16-04-0317
Abstract: Platelet defects due to hyper-responsive GPIbα causing enhanced VWF interaction, counter-intuitively result in bleeding rather than thrombosis. The historical explanation of platelet/VWF clearance fails to explain mechanisms of impaired haemostasis particularly in light of reported… read more here.
Keywords: thrombosis; haemostasis; gpib; impaired vivo ... See more keywords