Association of Modifiable Lifestyle Factors With Cortical Amyloid Burden and Cerebral Glucose Metabolism in Older Adults With Mild Cognitive Impairment
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.5719
Abstract: Key Points Question Are modifiable lifestyle factors associated with cortical amyloid burden or cerebral glucose metabolism in older adults with mild cognitive impairment? Findings This cohort study included 118 older adults with mild cognitive impairment… read more here.
Keywords: adults mild; cognitive impairment; impairment; cerebral glucose ... See more keywords
Late-onset Cognitive Impairment and Modifiable Risk Factors in Adult Childhood Cancer Survivors
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DOI: 10.1001/jamanetworkopen.2023.16077
Abstract: Key Points Question Are adult survivors of childhood cancer at risk for new-onset neurocognitive impairments that outpace those associated with typical aging? Findings In this cohort study of 2375 adult survivors of childhood cancer and… read more here.
Keywords: new onset; impairment; risk; adult survivors ... See more keywords
Association of Elevated Amyloid and Tau Positron Emission Tomography Signal With Near-Term Development of Alzheimer Disease Symptoms in Older Adults Without Cognitive Impairment.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2022.2379
Abstract: Importance National Institute on Aging-Alzheimer's Association (NIA-AA) workgroups have proposed biological research criteria intended to identify individuals with preclinical Alzheimer disease (AD). Objective To assess the clinical value of these biological criteria to identify older… read more here.
Keywords: near term; tau; without cognitive; alzheimer disease ... See more keywords
Population Prevalence of Vision Impairment in US Adults 71 Years and Older: The National Health and Aging Trends Study.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2022.5840
Abstract: Importance Existing estimates of the prevalence of vision impairment (VI) in the United States are based on self-reported survey data or measures of visual function that are at least 14 years old. Older adults are… read more here.
Keywords: adults years; years older; prevalence; impairment ... See more keywords
Relationship between impaired work function and coping behaviors in workers with low back pain
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DOI: 10.1002/1348-9585.12272
Abstract: Abstract Objectives The aim of the present study was to clarify the relationship between work functional impairment levels and three coping behaviors of workers with low back pain, which were about seeking medical attention, taking… read more here.
Keywords: work; coping behaviors; work function; impairment ... See more keywords
Associations between coronary heart disease and risk of cognitive impairment: A meta‐analysis
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DOI: 10.1002/brb3.2108
Abstract: Several studies have demonstrated that coronary heart disease (CHD) is a high risk factor for cognitive impairment, whereas other studies showed that there was no association between cognitive impairment and CHD. The relationship between CHD… read more here.
Keywords: risk; heart disease; cognitive impairment; impairment ... See more keywords
Improvement of poststroke cognitive impairment by intermittent theta bursts: A double‐blind randomized controlled trial
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2569
Abstract: Intermittent theta burst stimulation (iTBS) is known to improve cognitive impairment caused by Alzheimer's disease and Parkinson's disease, but studies are lacking with respect to the efficacy of iTBS on poststroke cognitive impairment (PSCI). read more here.
Keywords: impairment; cognitive impairment; intermittent theta; poststroke cognitive ... See more keywords
Association of neck circumference and cognitive impairment among Chinese elderly
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DOI: 10.1002/brb3.937
Abstract: To investigate the association between neck circumference (NC) and cognitive impairment and interactions between relevant variables to the risk of cognitive impairment. read more here.
Keywords: association neck; cognitive impairment; impairment; neck circumference ... See more keywords
Association between serum cystatin C and early impairment of cardiac function and structure in type 2 diabetes patients with normal renal function
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DOI: 10.1002/clc.23920
Abstract: Type 2 diabetes mellitus (T2DM) patients may have cardiac remodeling and dysfunction from the early stage of disease. This study aimed to determine the association between cystatin C (CysC) and early cardiac functional or structural… read more here.
Keywords: impairment; function; type diabetes; association serum ... See more keywords
Rimegepant 75 mg in Subjects With Hepatic Impairment: Results of a Phase 1, Open-Label, Single-Dose, Parallel-Group Study.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical pharmacology in drug development"
DOI: 10.1002/cpdd.1244
Abstract: Rimegepant is a small-molecule calcitonin gene-related peptide receptor antagonist (gepant) with demonstrated efficacy and safety in the acute and preventive treatment of migraine. Here, we report the pharmacokinetics and safety of a single 75-mg oral… read more here.
Keywords: label single; rimegepant subjects; hepatic impairment; impairment ... See more keywords
Effect of Renal or Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of Intravenous Rivipansel
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DOI: 10.1002/cpdd.842
Abstract: Two studies evaluated the effects of renal and hepatic impairment on pharmacokinetics and safety of rivipansel (NCT02813798, NCT02871570). A single intravenous 840‐mg rivipansel dose was administered to subjects with renal impairment or normal renal function… read more here.
Keywords: rivipansel; renal hepatic; hepatic impairment; impairment pharmacokinetics ... See more keywords