Articles with "impairment healthy" as a keyword



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A Phase 1 Study to Evaluate the Pharmacokinetics and Safety of Cabotegravir in Patients With Hepatic Impairment and Healthy Matched Controls

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Published in 2019 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.655

Abstract: Cabotegravir is an investigational integrase inhibitor in development for the treatment and pre‐exposure prophylaxis of HIV‐1 infection. Liver disease is a major cause of morbidity and mortality in HIV‐infected individuals and can impact the pharmacokinetics… read more here.

Keywords: cabotegravir; phase study; impairment healthy; hepatic impairment ... See more keywords