Articles with "impairs cholangiocarcinoma" as a keyword



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Inhibition of XPO1 impairs cholangiocarcinoma cell proliferation by triggering p53 intranuclear accumulation

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Published in 2022 at "Cancer Medicine"

DOI: 10.1002/cam4.5322

Abstract: XPO1 mediates the nuclear export of several proteins, mainly tumor suppressors. KPT‐330 (Selinexor) is a selective inhibitor of XPO1 that has demonstrated good therapeutic effects in hematologic cancers. read more here.

Keywords: cell proliferation; xpo1; cholangiocarcinoma cell; inhibition xpo1 ... See more keywords