Scaling up disease model discovery
Sign Up to like & getrecommendations! Published in 2017 at "Lab Animal"
DOI: 10.1038/laban.1342
Abstract: data and ranks their mutant lines as models for human diseases. “The goal is to use phenotype mapping along with whole genome variant prioritization and filtering to land on the most likely causative variant along… read more here.
Keywords: disease model; mouse genome; disease; impc ... See more keywords
NIH Knockout Mouse Phenotyping Program (KOMP2) and IMPC: Database to Discover New Roles of Genes in Cardiovascular Physiology and Disease.
Sign Up to like & getrecommendations! Published in 2019 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00011.2019
Abstract: The collaborative goal of NIH Knockout Mouse Phenotyping Program (KOMP2) and International Knockout Mouse Phenotyping Consortium (IMPC) is to discover functional insight for every gene in the mouse genome by 2021, by generating and systematically… read more here.
Keywords: physiology; gene; impc; knockout mouse ... See more keywords
Analysis of Prognostic Factors and Construction of Prognostic Models for Invasive Micropapillary Carcinoma of the Breast
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/1072218
Abstract: Objective To compare and analyze the clinical characteristics of invasive micropapillary carcinoma (IMPC) of the breast (IMPC-B) and invasive ductal carcinoma (IDC) of the breast (IDC-B) and establish a prognostic model of IMPC-B. Methods We… read more here.
Keywords: breast; impc; risk; stage ... See more keywords
Overexpression of β1 integrin contributes to polarity reversal and a poor prognosis of breast invasive micropapillary carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.22774
Abstract: Invasive micropapillary carcinoma (IMPC) of the breast is a highly aggressive breast cancer. Polarity reversal exemplified by cluster growth is hypothesized to contribute to the invasiveness and metastasis of IMPC. In this study, we demonstrate… read more here.
Keywords: breast; overexpression integrin; impc; polarity reversal ... See more keywords
The Clinicopathological Characteristics of Pure and Mixed Invasive Micropapillary Breast Carcinomas: A Single Center Experience
Sign Up to like & getrecommendations! Published in 2022 at "Balkan Medical Journal"
DOI: 10.4274/balkanmedj.galenos.2022.2022-4-7
Abstract: Background: Invasive micropapillary carcinoma (IMPC) is a rare tumor of the breast. IMPC can be classified as a pure or mixed type based on the extent of micropapillary differentiation. Aims: To evaluate the prognostic importance… read more here.
Keywords: mixed impc; breast; impc; invasive micropapillary ... See more keywords