IMPDH2's Central Role in Cellular Growth and Diseases: A Potential Therapeutic Target
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DOI: 10.1111/cpr.70031
Abstract: IMPDH2 is a rate‐limiting enzyme in guanine nucleotide biosynthesis. It plays diverse roles in various physiological and pathological processes: nucleotide metabolism, inflammation, immune function, ribosomal stress. Structural or regulatory alterations in IMPDH2 are linked to… read more here.
Keywords: role cellular; cellular growth; central role; target ... See more keywords