A model-free framework for evaluating the reliability of a new device with multiple imperfect reference standards.
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DOI: 10.1093/biomtc/ujaf025
Abstract: A common practice for establishing the reliability of a new computer-aided diagnostic (CAD) device is to evaluate how well its clinical measurements agree with those of a gold standard test. However, in many clinical studies,… read more here.
Keywords: device; reference; imperfect reference; reliability ... See more keywords
Estimation of diagnostic accuracy of a combination of continuous biomarkers allowing for conditional dependence between the biomarkers and the imperfect reference-test.
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DOI: 10.1111/biom.12583
Abstract: Estimating biomarker-index accuracy when only imperfect reference-test information is available is usually performed under the assumption of conditional independence between the biomarker and imperfect reference-test values. We propose to define a latent normally-distributed tolerance-variable underlying… read more here.
Keywords: reference test; conditional dependence; accuracy; imperfect reference ... See more keywords