Sophocarpine attenuates wear particle‐induced implant loosening by inhibiting osteoclastogenesis and bone resorption via suppression of the NF‐κB signalling pathway in a rat model
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DOI: 10.1111/bph.14092
Abstract: Aseptic prosthesis loosening, caused by wear particles, is one of the most common causes of arthroplasty failure. Extensive and over‐activated osteoclast formation and physiological functioning are regarded as the mechanism of prosthesis loosening. Therapeutic modalities… read more here.
Keywords: bone resorption; prosthesis loosening; implant loosening;
Adverse Events due to Lack of Precision in Total Hip Arthroplasty: The Potential of Provocation-Based CT for Diagnosis of Implant Loosening
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DOI: 10.1155/2021/8836687
Abstract: Adverse events in total hip replacement (THR) may have several origins, one being lack of precision in diagnosis and/or during surgery. This study describes the pattern and frequency of avoidable injuries in THR and the… read more here.
Keywords: diagnosis; implant loosening; lack precision; adverse events ... See more keywords
Is prophylaxis for heterotopic ossification with radiation therapy after THR associated with early loosening or carcinogenesis?
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DOI: 10.1177/1120700019842724
Abstract: Introduction: Heterotopic ossification may develop after major hip surgeries, thus preventive strategies including radiation therapy and non steroid anti-inflammatory drugs are commonly employed. There are certain concerns regarding the effects of radiation therapy on implant… read more here.
Keywords: implant loosening; heterotopic ossification; radiation therapy; radiation ... See more keywords
Additive Effect of Parathyroid Hormone and Zoledronate Acid on Prevention Particle Wears-Induced Implant Loosening by Promoting Periprosthetic Bone Architecture and Strength in an Ovariectomized Rat Model
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DOI: 10.3389/fendo.2022.871380
Abstract: Implant-generated particle wears are considered as the major cause for the induction of implant loosening, which is more susceptible to patients with osteoporosis. Monotherapy with parathyroid hormone (PTH) or zoledronate acid (ZOL) has been proven… read more here.
Keywords: effect; implant loosening; bone; pth zol ... See more keywords
Dental and Orthopaedic Implant Loosening: Overlap in Gene Expression Regulation
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DOI: 10.3389/fimmu.2022.820843
Abstract: Objectives Endoprosthetic loosening still plays a major role in orthopaedic and dental surgery and includes various cellular immune processes within peri-implant tissues. Although the dental and orthopaedic processes vary in certain parts, the clinical question… read more here.
Keywords: transwell; expression; implant loosening; gene ... See more keywords
The effect of surgical suture material on osteoclast generation and implant-loosening
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DOI: 10.7150/ijms.50270
Abstract: Background: Implant loosening - either infectious or aseptic- is a still a major complication in the field of orthopaedic surgery. In both cases, a pro-inflammatory peri-prosthetic environment is generated by the immune system - either… read more here.
Keywords: surgical suture; implant loosening; generation; suture ... See more keywords