1α,25-Dihydroxyvitamin D3 increases implant osseointegration in diabetic mice partly through FoxO1 inactivation in osteoblasts.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.10.024
Abstract: Oral implant osseointegration is delayed by hyperglycemia-generated oxidative stress (OS). Forkhead transcription factor 1 (FoxO1) is known to be viewed as a sensor to OS since reactive oxide species like H2O2 regulates its activity. We… read more here.
Keywords: bone; mice; diabetic mice; implant osseointegration ... See more keywords
Evaluation of the effects of topically applied simvastatin on titanium implant osseointegration.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of oral biology and craniofacial research"
DOI: 10.1016/j.jobcr.2020.04.004
Abstract: Objective The aim of this study was to evaluate the effect of topical simvastatin on the osseointegration of machined-surface titanium implants. Material & methods Sixteen female Sprague-Dawley rats were used in this study in a… read more here.
Keywords: titanium implant; group; bone; titanium ... See more keywords
Design/exploration and verification of an electromagnetic probe for assessing dental implant osseointegration
Sign Up to like & getrecommendations! Published in 2021 at "Measurement"
DOI: 10.1016/j.measurement.2021.109054
Abstract: Abstract Osseointegration is the key to the success of surgery of dental implantation. In this study, we proposed, implemented and explored a handheld and noncontact electromagnetic-type stability assessment device for the use after surgery. The… read more here.
Keywords: design exploration; verification electromagnetic; exploration verification; implant osseointegration ... See more keywords
The effect of insulin and kruppel like factor 10 on osteoblasts in the dental implant osseointegration in diabetes mellitus patients
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2084534
Abstract: ABSTRACT Diabetes mellitus, metabolic disease, is characterized by chronic hyperglycemia. Patients with diabetes mellitus are susceptible to infection and therefore have a higher prevalence and progression rate of periodontal disease. We aimed to study the… read more here.
Keywords: klf10; dental implant; expression; implant osseointegration ... See more keywords
Biological Response to Recombinant Human Bone Morphogenetic Protein-2 on Bone-Implant Osseointegration in Ovariectomized Experimental Design
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Craniofacial Surgery"
DOI: 10.1097/scs.0000000000004992
Abstract: Objective: The aim of this study is to investigate the effects of recombinant human bone morphogenetic protein-2 (rhBMP-2) on bone-implant osteointegration in osteoporotic rats. Materials and Methods: Thirty-six female Wistar rats were randomly divided into… read more here.
Keywords: implant osseointegration; bone implant; bone; ovx rhbmp ... See more keywords
α-KG Up-regulates Autophagic Activity in Peri-implant Environment and Enhances Dental Implant Osseointegration in Osteoporotic Mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of clinical periodontology"
DOI: 10.1111/jcpe.13784
Abstract: AIM The osseointegration of dental implants is impaired among patients with osteoporosis, leading to significantly higher failure rate. This study set out to investigate the potential effects of alpha-ketoglutarate (α-KG) on implant osseointegration in an… read more here.
Keywords: autophagic activity; osseointegration; dental implant; implant osseointegration ... See more keywords
Impaired dental implant osseointegration in rat with streptozotocin-induced diabetes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of periodontal research"
DOI: 10.1111/jre.12972
Abstract: OBJECTIVE Few studies have reported on the impact of oxidative stress on the dental implant failure. The aim of this study was to investigate the impact of hyperglycemia-induced oxidative stress on dental implant osseointegration in… read more here.
Keywords: streptozotocin induced; osseointegration; oxidative stress; dental implant ... See more keywords
Effects of Metformin on the Osteogenesis of Alveolar BMSCs from Diabetic Patients and Implant Osseointegration in Rats.
Sign Up to like & getrecommendations! Published in 2021 at "Oral diseases"
DOI: 10.1111/odi.13808
Abstract: OBJECTIVES This study aimed to explore the effects of metformin on osteogenic differentiation of alveolar bone marrow mesenchymal stem cells (BMSCs) from type-2 diabetes mellitus (T2DM) patients (DM-BMSCs) and implant osseointegration in rats, screen the… read more here.
Keywords: implant osseointegration; osseointegration rats; osteogenesis; bmscs ... See more keywords
Alveolar Bone Marrow Gli1+ Stem Cells Support Implant Osseointegration.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of dental research"
DOI: 10.1177/00220345211013722
Abstract: Osseointegration is the key issue for implant success. The in vivo properties of cell populations driving the osseointegration process have remained largely unknown. In the current study, using tissue clearing-based 3-dimensional imaging and transgenic mouse… read more here.
Keywords: gli1 cells; bone; alveolar bone; osseointegration ... See more keywords
PTPN2 improves implant osseointegration in T2DM via inducing the dephosphorylation of ERK
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Biology and Medicine"
DOI: 10.1177/1535370219883419
Abstract: Type 2 diabetes mellitus (T2DM) is considered to compromise implant osseointegration. Protein tyrosine phosphatase non-receptor type 2 (PTPN2) regulates glucose metabolism, systemic inflammation, and bone regeneration. This study aimed to investigate the role of PTPN2… read more here.
Keywords: ptpn2; osseointegration t2dm; high glucose; osseointegration ... See more keywords
Hormone and implant osseointegration: Elaboration of the relationship among function, preclinical, and clinical practice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.965753
Abstract: As clusters of peptides or steroids capable of high-efficiency information transmission, hormones have been substantiated to coordinate metabolism, growth, development, and other physiological processes, especially in bone physiology and repair metabolism. In recent years, the… read more here.
Keywords: hormone implant; hormone; elaboration relationship; osseointegration elaboration ... See more keywords