The Implication of Topoisomerase II Inhibitors in Synthetic Lethality for Cancer Therapy
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DOI: 10.3390/ph16010094
Abstract: DNA topoisomerase II (Top2) is essential for all eukaryotic cells in the regulation of DNA topology through the generation of temporary double-strand breaks. Cancer cells acquire enhanced Top2 functions to cope with the stress generated… read more here.
Keywords: implication topoisomerase; dna; synthetic lethality; top2 ... See more keywords