Implications of FBXW7 in Neurodevelopment and Neurodegeneration: Molecular Mechanisms and Therapeutic Potential
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DOI: 10.3389/fncel.2021.736008
Abstract: The ubiquitin-proteasome system (UPS) mediated protein degradation is crucial to maintain quantitive and functional homeostasis of diverse proteins. Balanced cellular protein homeostasis controlled by UPS is fundamental to normal neurological functions while impairment of UPS… read more here.
Keywords: neurodevelopment neurodegeneration; neurodegeneration molecular; molecular mechanisms; fbxw7 neurodevelopment ... See more keywords