Articles with "implications hypermutation" as a keyword



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Abstract 5705: Mechanisms and therapeutic implications of hypermutation in gliomas

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Published in 2020 at "Cancer Research"

DOI: 10.1158/1538-7445.am2020-5705

Abstract: High tumor mutational burden (hypermutation) is observed in some gliomas; however, its mechanisms of development and whether it predicts immunotherapy response are poorly understood. Here, we comprehensively analyze the molecular determinants of mutational burden and… read more here.

Keywords: gliomas; implications hypermutation; mechanisms therapeutic; therapeutic implications ... See more keywords