Sumoylation: Implications for Neurodegenerative Diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-50044-7_16
Abstract: The covalent posttranslational modifications of proteins are critical events in signaling cascades that enable cells to efficiently, rapidly and reversibly respond to extracellular stimuli. This is especially important in the CNS where the processes affecting… read more here.
Keywords: sumoylation; sumoylation implications; neurodegenerative diseases; implications neurodegenerative ... See more keywords
Mitohormesis; Potential implications in neurodegenerative diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Mitochondrion"
DOI: 10.1016/j.mito.2020.11.011
Abstract: Mitochondrial dysfunction is known to be associated with neurodegenerative diseases (NDDs), which is a major burden on the society. Therefore, understanding the regulation of mitochondrial dysfunctions and its implication in neurodegeneration has been major goal… read more here.
Keywords: mitohormesis; neurodegenerative diseases; implications neurodegenerative; neurodegeneration ... See more keywords
Neuronal proteins as targets of 3-hydroxykynurenine: Implications in neurodegenerative diseases.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00265
Abstract: The neurotoxic activity of the tryptophan metabolite 3-hydroxykynurenine (3OHKyn) in neurodegenerative disorders as Parkinson's and Alzheimer's diseases, is related to oxidative stress and 3OHKyn interaction with cellular proteins. The pattern of protein modification induced by… read more here.
Keywords: targets hydroxykynurenine; hydroxykynurenine implications; neurodegenerative diseases; implications neurodegenerative ... See more keywords
Neuronal biomolecular condensates and their implications in neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2023.1145420
Abstract: Biomolecular condensates are subcellular organizations where functionally related proteins and nucleic acids are assembled through liquid–liquid phase separation, allowing them to develop on a larger scale without a membrane. However, biomolecular condensates are highly vulnerable… read more here.
Keywords: neurodegenerative diseases; neuronal biomolecular; implications neurodegenerative; biomolecular ... See more keywords