Classification of KRAS-Activating Mutations and the Implications for Therapeutic Intervention.
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DOI: 10.1158/2159-8290.cd-22-0035
Abstract: Members of the family of RAS proto-oncogenes, discovered just over 40 years ago, were among the first cancer-initiating genes to be discovered. Of the three RAS family members, KRAS is the most frequently mutated in… read more here.
Keywords: classification kras; kras activating; activating mutations; mutations implications ... See more keywords
The Juggernaut of Adaptive Metabolism in Cancers: Implications and Therapeutic Targets
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DOI: 10.3390/cancers14215202
Abstract: The disease of cancer instills a sense of fear and dread among patients and the next of kin who are indirectly affected by the deteriorating quality of life of their loved ones [...]. read more here.
Keywords: adaptive metabolism; implications therapeutic; cancers implications; therapeutic targets ... See more keywords