Pathophysiologic implications and therapeutic potentials of telocytes in multiorgan fibrosis
Sign Up to like & getrecommendations! Published in 2025 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000001116
Abstract: Purpose of review Telocytes (TCs) are unique stromal cells with distinctive morphology, ultrastructural features, and intercellular communication abilities. Accumulating evidence supports their critical roles in tissue homeostasis, regeneration, and stem cell niche maintenance through both… read more here.
Keywords: pathophysiologic implications; multiorgan fibrosis; implications therapeutic; cell ... See more keywords
Classification of KRAS-Activating Mutations and the Implications for Therapeutic Intervention.
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DOI: 10.1158/2159-8290.cd-22-0035
Abstract: Members of the family of RAS proto-oncogenes, discovered just over 40 years ago, were among the first cancer-initiating genes to be discovered. Of the three RAS family members, KRAS is the most frequently mutated in… read more here.
Keywords: classification kras; kras activating; activating mutations; mutations implications ... See more keywords
The Juggernaut of Adaptive Metabolism in Cancers: Implications and Therapeutic Targets
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DOI: 10.3390/cancers14215202
Abstract: The disease of cancer instills a sense of fear and dread among patients and the next of kin who are indirectly affected by the deteriorating quality of life of their loved ones [...]. read more here.
Keywords: adaptive metabolism; implications therapeutic; cancers implications; therapeutic targets ... See more keywords