Protein translocation in mitochondria: Sorting out the Toms, Tims, Pams, Sams and Mia.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14614
Abstract: Mitochondria contain 902 (yeast) to 1.136 (mouse, humans) verified proteins. Except for a very small number of mitochondrially encoded core components of the respiratory chain, mitochondrial proteins are encoded by nuclear genes and synthesized in… read more here.
Keywords: protein translocation; sorting toms; import; mitochondrial import ... See more keywords
Light‐Dependent Cytoplasmic Recruitment Enhances the Dynamic Range of a Nuclear Import Photoswitch
Sign Up to like & getrecommendations! Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201700681
Abstract: Cellular signal transduction is often regulated at multiple steps to achieve more complex logic or precise control of a pathway. For instance, some signaling mechanisms couple allosteric activation with localization to achieve high signal to… read more here.
Keywords: import; import photoswitch; dynamic range; nuclear import ... See more keywords
Hormone-Inducible Transport Reporter Assay to Study Nuclear Import Defects in Neurodegenerative Diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2337-4_5
Abstract: In the recent years, defective nuclear import has emerged as an important pathomechanism of neurodegenerative diseases, particularly in amyotrophic lateral sclerosis (ALS). Here, specific nuclear RNA binding proteins (RBPs) mislocalize and aggregate in the cytoplasm… read more here.
Keywords: import; hormone inducible; nuclear import; inducible transport ... See more keywords
Peroxisomal Membrane and Matrix Protein Import Using a Semi-Intact Mammalian Cell System.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6937-1_20
Abstract: Peroxisomes are essential intracellular organelles that catalyze a number of essential metabolic pathways including β-oxidation of very long chain fatty acids, synthesis of plasmalogen, bile acids, and generation and degradation of hydrogen peroxide. These peroxisomal… read more here.
Keywords: protein import; system; import; semi intact ... See more keywords
The import price index with trade barriers: theory and evidence
Sign Up to like & getrecommendations! Published in 2017 at "Empirical Economics"
DOI: 10.1007/s00181-015-1064-2
Abstract: The standard economic import price index hinges on an assumption of free trade. Applying the index to situations with barriers to trade yields biased results compared to a true import price index. To circumvent this… read more here.
Keywords: index; price index; import price; import ... See more keywords
Automating Import and Reconciliation of Outside Examinations Submitted to an Academic Radiology Department
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Digital Imaging"
DOI: 10.1007/s10278-019-00291-3
Abstract: Although advances in electronic image sharing have made continuity of patient care easier, currently, the majority of outside studies are received on CD. At our institution, there were 9 full-time employees (FTE) at three locations… read more here.
Keywords: import reconciliation; radiology; import; reconciliation outside ... See more keywords
Russian Chemical Fibre Industry in 2015
Sign Up to like & getrecommendations! Published in 2017 at "Fibre Chemistry"
DOI: 10.1007/s10692-017-9798-6
Abstract: The domestic chemical fibre industry lags, as before, behind the pre-restructuring period in production and consumption volumes by almost five times. This is still very far from the optimistic predictions often heard at forums, conferences,… read more here.
Keywords: production; fibre; industry; import ... See more keywords
Chloroplast transport and import
Sign Up to like & getrecommendations! Published in 2018 at "Photosynthesis Research"
DOI: 10.1007/s11120-018-0593-x
Abstract: As is well known to readers of this Special Issue, chloroplasts possess their own genetic material and are capable of a limited amount of autonomous protein synthesis. Nevertheless, more than 95% of the protein complement… read more here.
Keywords: protein; issue; article; transport ... See more keywords
Importin KPNA2 confers HIV-1 pre-integration complex nuclear import by interacting with the capsid protein.
Sign Up to like & getrecommendations! Published in 2022 at "Antiviral research"
DOI: 10.1016/j.antiviral.2022.105289
Abstract: For human immunodeficiency virus 1 (HIV-1) to infect non-dividing cells, pre-integration complex (PIC) must be transported into the nucleus within the replication cycle. We previously reported that the karyopherin β1 (KPNB1)-nucleoporin Pom121 pathway, related to… read more here.
Keywords: import; pic nuclear; nuclear import; kpna2 ... See more keywords
Dynamic Phosphorylation of the C Terminus of Hsp70 Regulates the Mitochondrial Import of SOD2 and Redox Balance.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.11.015
Abstract: The import of superoxide dismutase-2 (SOD2) into mitochondria is vital for the survival of eukaryotic cells. SOD2 is encoded within the nuclear genome and translocated into mitochondria for activation after translation in the cytosol. The… read more here.
Keywords: hsp70; sod2; import; redox balance ... See more keywords
Systematic Identification of Regulators of Oxidative Stress Reveals Non-canonical Roles for Peroxisomal Import and the Pentose Phosphate Pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.01.013
Abstract: Reactive oxygen species (ROS) play critical roles in metabolism and disease, yet a comprehensive analysis of the cellular response to oxidative stress is lacking. To systematically identify regulators of oxidative stress, we conducted genome-wide Cas9/CRISPR and shRNA… read more here.
Keywords: phosphate pathway; regulators oxidative; pentose phosphate; import ... See more keywords