Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.03.003
Abstract: Liquid-liquid phase separation (LLPS) is believed to underlie formation of biomolecular condensates, cellular compartments that concentrate macromolecules without surrounding membranes. Physical mechanisms that control condensate formation/dissolution are poorly understood. The RNA-binding protein fused in sarcoma… read more here.
Keywords: phase separation; fus; receptor inhibits; import receptor ... See more keywords
The nuclear import receptor importin-7 targets HPV from the Golgi to the nucleus to promote infection
Sign Up to like & getrecommendations! Published in 2025 at "Science Advances"
DOI: 10.1126/sciadv.adz6792
Abstract: During human papillomavirus (HPV) entry, the virus exploits COPI-dependent retrograde transport to cross the Golgi apparatus before reaching the nucleus to cause infection. How HPV enters the nucleus after exiting the Golgi is unclear, although… read more here.
Keywords: hpv; infection; import receptor; golgi nucleus ... See more keywords