Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
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DOI: 10.1016/j.cell.2018.03.003
Abstract: Liquid-liquid phase separation (LLPS) is believed to underlie formation of biomolecular condensates, cellular compartments that concentrate macromolecules without surrounding membranes. Physical mechanisms that control condensate formation/dissolution are poorly understood. The RNA-binding protein fused in sarcoma… read more here.
Keywords: phase separation; fus; receptor inhibits; import receptor ... See more keywords