Deep mutational scanning of S. pyogenes Cas9 reveals important functional domains
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DOI: 10.1038/s41598-017-17081-y
Abstract: RNA-guided endonucleases (RGENs) have invigorated the field of site-specific nucleases. The success of Streptococcus pyogenes Cas9 (SpCas9) has led to the discovery of several other CRISPR-associated RGENs. As more RGENs become available, it will be… read more here.
Keywords: pyogenes cas9; deep mutational; important functional; mutational scanning ... See more keywords