Robust structured heterogeneity analysis approach for high‐dimensional data
Sign Up to like & getrecommendations! Published in 2022 at "Statistics in Medicine"
DOI: 10.1002/sim.9414
Abstract: Revealing relationships between genes and disease phenotypes is a critical problem in biomedical studies. This problem has been challenged by the heterogeneity of diseases. Patients of a perceived same disease may form multiple subgroups, and… read more here.
Keywords: heterogeneity; important genes; heterogeneity analysis; robust structured ... See more keywords
A Selection of Important Genes and Their Correlated Behavior in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Alzheimer's Disease"
DOI: 10.3233/jad-170799
Abstract: In 2017, approximately 5 million Americans were living with Alzheimer’s disease (AD), and it is estimated that by 2050 this number could increase to 16 million. In this study, we apply mathematical optimization to approach… read more here.
Keywords: alzheimer disease; genes correlated; disease selection; disease ... See more keywords