Protofibrils of Amyloid-β are Important Targets of a Disease-Modifying Approach for Alzheimer’s Disease
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DOI: 10.3390/ijms21030952
Abstract: Worldwide, Alzheimer’s disease (AD) is the most common age-related neurodegenerative disease and is characterized by unique pathological hallmarks in the brain, including plaques composed of amyloid β-protein (Aβ) and neurofibrillary tangles of tau protein. Genetic… read more here.
Keywords: targets disease; alzheimer disease; disease; protofibrils amyloid ... See more keywords
Nogo-A and LINGO-1: Two Important Targets for Remyelination and Regeneration
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DOI: 10.3390/ijms24054479
Abstract: Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) that causes progressive neurological disability in most patients due to neurodegeneration. Activated immune cells infiltrate the CNS, triggering an inflammatory cascade that… read more here.
Keywords: regeneration; nogo lingo; lingo two; remyelination regeneration ... See more keywords