Immune Monitoring Reveals Fusion Peptide Priming to Imprint Cross-Clade HIV-Neutralizing Responses with a Characteristic Early B Cell Signature.
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DOI: 10.1016/j.celrep.2020.107981
Abstract: The HIV fusion peptide (FP) is a promising vaccine target. FP-directed monoclonal antibodies from vaccinated macaques have been identified that neutralize up to ∼60% of HIV strains; these vaccinations, however, have involved ∼1 year with… read more here.
Keywords: immune monitoring; fusion peptide; imprint cross; neutralizing responses ... See more keywords