Identification and Comparison of Imprinted Genes Across Plant Species.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0179-2_13
Abstract: Genomic imprinting is a phenomenon that occurs in flowering plants and mammals, whereby a gene is expressed in a parent-of-origin-specific manner. Although imprinting has now been examined genome-wide in a number of species using RNA-seq,… read more here.
Keywords: genes across; plant; imprinted genes; across plant ... See more keywords
Deregulation of imprinted genes expression and epigenetic regulators in placental tissue from intrauterine growth restriction
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-020-02047-3
Abstract: Purpose Intrauterine growth restriction (IUGR) is a fetal growth complication that can be caused by ineffective nutrient transfer from the mother to the fetus via the placenta. Abnormal placental development and function have been correlated… read more here.
Keywords: epigenetic regulators; restriction; methylation; imprinted genes ... See more keywords
Imprinted genes in clinical exome sequencing: Review of 538 cases and exploration of mouse-human conservation in the identification of novel human disease loci.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medical genetics"
DOI: 10.1016/j.ejmg.2020.103903
Abstract: Human imprinting disorders cause a range of dysmorphic and neurocognitive phenotypes, and they may elude traditional molecular diagnosis such exome sequencing. The discovery of novel disorders related to imprinted genes has lagged behind traditional Mendelian… read more here.
Keywords: exome sequencing; imprinted genes; clinical exome; conservation ... See more keywords
Imprinted genes and the regulation of placental endocrine function: Pregnancy and beyond.
Sign Up to like & getrecommendations! Published in 2017 at "Placenta"
DOI: 10.1016/j.placenta.2017.01.099
Abstract: Genomic imprinting is an epigenetic process responsible for the monoallelic expression of a subset of genes in mammals. Imprinted genes have been demonstrated to play important functions prenatally regulating fetal growth and placental development with… read more here.
Keywords: pregnancy; imprinted genes; placental endocrine; regulation placental ... See more keywords
Paternally expressed imprinted genes associate with hybridization barriers in Capsella
Sign Up to like & getrecommendations! Published in 2018 at "Nature Plants"
DOI: 10.1038/s41477-018-0161-6
Abstract: Hybrid seed lethality is a widespread type of reproductive barrier among angiosperm taxa1,2 that contributes to species divergence by preventing gene flow between natural populations3,4. Besides its ecological importance, it is an important obstacle to… read more here.
Keywords: capsella; seed; imprinted genes; effective ploidy ... See more keywords
Embryonic germ cell extracts erase imprinted genes and improve the efficiency of induced pluripotent stem cells
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29339-0
Abstract: Patient-specific induced pluripotent stem cells (iPSCs) have the potential to be useful in the treatment of human diseases. While prior studies have reported multiple methods to generate iPSCs, DNA methylation continues to limit the totipotency… read more here.
Keywords: imprinted genes; embryonic germ; pluripotent stem; induced pluripotent ... See more keywords
Advances in DNA methylation of imprinted genes and folic acid regulation of growth and development.
Sign Up to like & getrecommendations! Published in 2024 at "Epigenomics"
DOI: 10.1080/17501911.2024.2384833
Abstract: DNA methylation is closely related to folate levels and acts as a mechanism linking developmental disorders to chronic diseases. Folic acid supplementation can impact DNA methylation levels of imprinted genes crucial for neonatal development. Imprinted… read more here.
Keywords: folic acid; dna methylation; imprinted genes; growth ... See more keywords
Overexpression of Placenta-Specific Noncanonical Imprinted Genes Causes Placental Enlargement in Intersubspecific Hybrid Mice.
Sign Up to like & getrecommendations! Published in 2025 at "Biology of reproduction"
DOI: 10.1093/biolre/ioaf259
Abstract: Placental enlargement in somatic cell nuclear transfer (SCNT)-derived mice is attributed to biallelic expression of noncanonical (H3K27me3-dependent) imprinted genes owing to loss of imprinting (LOI). Here, we investigated whether a similar mechanism underlies placental enlargement… read more here.
Keywords: noncanonical imprinted; placental enlargement; enlargement intersubspecific; imprinted genes ... See more keywords
Identification of imprinted genes in the skeletal muscle of newborn piglets by high-throughput sequencing.
Sign Up to like & getrecommendations! Published in 2022 at "Animal genetics"
DOI: 10.1111/age.13212
Abstract: Imprinted genes - exhibiting parent-specific transcription - play essential roles in the process of mammalian development and growth. Skeletal muscle growth is crucial for meat production. To further understand the role of imprinted genes during… read more here.
Keywords: growth; muscle; expressed imprinted; genes skeletal ... See more keywords
PMM2 and NARFL are paternally imprinted genes in bovines.
Sign Up to like & getrecommendations! Published in 2022 at "Animal genetics"
DOI: 10.1111/age.13247
Abstract: In mammals, imprinted genes are required for both fetal development and postnatal growth. A novel candidate imprinted locus was found on human chromosome 16, and maternal uniparental disomy of this locus can cause a lethal… read more here.
Keywords: paternally imprinted; genes bovines; region; pmm2 narfl ... See more keywords
Abstract 862: Multi-omic analysis of allelic expression patterns of imprinted and non-imprinted genes in cancer and their association with drug response
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-862
Abstract: Malignant cells undergo a broad array of epigenetic changes, including changes in imprinting patterns. In normal cells, imprinted genes have parent of origin-specific monoallelic expression, which is controlled via epigenetic mechanisms. Imprinted gene loci are… read more here.
Keywords: cancer; patterns imprinted; allelic expression; expression patterns ... See more keywords