Longitudinal Effects of Developmental Bisphenol A Exposure on Epigenome-Wide DNA Hydroxymethylation at Imprinted Loci in Mouse Blood
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Health Perspectives"
DOI: 10.1289/ehp3441
Abstract: Background: Epigenetic machinery plays an important role in genomic imprinting, a developmental process that establishes parent-of-origin–specific monoallelic gene expression. Although a number of studies have investigated the role of 5-methylcytosine in imprinting control, the contribution… read more here.
Keywords: mouse blood; exposure; bpa exposure; hmc ... See more keywords
Both Epimutations and Chromosome Aberrations Affect Multiple Imprinted Loci in Aggressive Wilms Tumors
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DOI: 10.3390/cancers12113411
Abstract: Simple Summary About 7% of all children’s malignancies are represented by the embryonal renal cancer Wilms tumor (WT). Since methylation imprinting alterations at multiple loci dictated by chromosome copy-number variations have been recently demonstrated in… read more here.
Keywords: chromosome aberrations; multiple imprinted; methylation; imprinted loci ... See more keywords
Defining Candidate Imprinted loci in Bos taurus
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DOI: 10.3390/genes14051036
Abstract: Using a whole-genome assembly of Bos taurus, I applied my bioinformatics strategy to locate candidate imprinting control regions (ICRs) genome-wide. In mammals, genomic imprinting plays essential roles in embryogenesis. In my strategy, peaks in plots… read more here.
Keywords: candidate imprinted; defining candidate; bos taurus; imprinted loci ... See more keywords