How can we improve the design of small molecules to target thioredoxin reductase for treating cancer?
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DOI: 10.1080/17460441.2021.1854220
Abstract: The ubiquitous thioredoxin reductase (TrxR, encoded by TXNRD gene) enzymes are essential to maintain the cellular redox homeostasis. The most outstanding function of TrxR is to keep its native subs... read more here.
Keywords: thioredoxin reductase; improve design; reductase; design small ... See more keywords