Targeting Complement C3a Receptor to Improve Outcome After Ischemic Brain Injury
Sign Up to like & getrecommendations! Published in 2021 at "Neurochemical Research"
DOI: 10.1007/s11064-021-03419-6
Abstract: Ischemic stroke is a major cause of disability. No efficient therapy is currently available, except for the removal of the occluding blood clot during the first hours after symptom onset. Loss of function after stroke… read more here.
Keywords: c3a receptor; improve outcome; outcome; outcome ischemic ... See more keywords
Therapeutic host-directed strategies to improve outcome in tuberculosis
Sign Up to like & getrecommendations! Published in 2019 at "Mucosal Immunology"
DOI: 10.1038/s41385-019-0226-5
Abstract: Bacille Calmette-Guérin (BCG) is the only licenced tuberculosis (TB) vaccine, but has limited efficacy against pulmonary TB disease development and modest protection against extrapulmonary TB. Preventative antibiotic treatment for Mycobacterium tuberculosis (Mtb) infections in high-prevalence… read more here.
Keywords: improve outcome; treatment; host directed; tuberculosis ... See more keywords
Promptly and appropriately treat SARS-CoV-2– related Guillain-Barre syndrome in a gravida to improve the outcome
Sign Up to like & getrecommendations! Published in 2023 at "Baylor University Medical Center Proceedings"
DOI: 10.1080/08998280.2023.2167185
Abstract: W ith interest we read the article by Mohamed et al about a 26-year-old primigravida in her 34th week of gestation who developed Guillain-Barre syndrome (GBS) 17 days after having tested positive for SARS-CoV-2. GBS… read more here.
Keywords: gbs; improve outcome; guillain barre; barre syndrome ... See more keywords
Fight INflammation to Improve outcome after aneurysmal Subarachnoid HEmorRhage (FINISHER) trial: Study protocol for a randomized controlled trial
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DOI: 10.1177/17474930221093501
Abstract: Rationale: Aneurysmal subarachnoid hemorrhage (SAH) has high morbidity and mortality. While the primary injury results from the initial bleeding cannot currently be influenced, secondary injury through vasospasm and delayed cerebral ischemia worsens outcome and might… read more here.
Keywords: outcome; aneurysmal subarachnoid; subarachnoid hemorrhage; improve outcome ... See more keywords
Glibenclamide does not improve outcome following severe collagenase-induced intracerebral hemorrhage in rats
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DOI: 10.1371/journal.pone.0252584
Abstract: Intracerebral hemorrhage (ICH) is a devastating insult with few effective treatments. Edema and raised intracranial pressure contribute to poor outcome after ICH. Glibenclamide blocks the sulfonylurea 1 transient receptor potential melastatin 4 (Sur1-Trpm4) channel implicated… read more here.
Keywords: following severe; glibenclamide; improve outcome; outcome ... See more keywords