Engineered pegRNAs improve prime editing efficiency.
Sign Up to like & getrecommendations! Published in 2021 at "Nature biotechnology"
DOI: 10.1038/s41587-021-01039-7
Abstract: Prime editing enables the installation of virtually any combination of point mutations, small insertions or small deletions in the DNA of living cells. A prime editing guide RNA (pegRNA) directs the prime editor protein to… read more here.
Keywords: editing efficiency; engineered pegrnas; improve prime; pegrnas improve ... See more keywords