Directed modification of l-LcLDH1, an l-lactate dehydrogenase from Lactobacillus casei, to improve its specific activity and catalytic efficiency towards phenylpyruvic acid.
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DOI: 10.1016/j.jbiotec.2018.05.011
Abstract: To improve the specific activity and catalytic efficiency of l-LcLDH1, an NADH-dependent allosteric l-lactate dehydrogenase from L. casei, towards phenylpyruvic acid (PPA), its directed modification was conducted based on the semi-rational design. The three variant… read more here.
Keywords: improve specific; activity catalytic; specific activity; catalytic efficiency ... See more keywords