Structural optimization of diphenylpyrimidine derivatives (DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B leukemia cell lines.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2016.11.047
Abstract: A new series of diphenylpyrimidine derivatives (DPPYs) bearing various aniline side chains at the C-2 position of pyrimidine core were synthesized as potent BTK inhibitors. Most of these inhibitors displayed improved activity against B leukemia… read more here.
Keywords: improved activity; derivatives dppys; diphenylpyrimidine derivatives; btk inhibitors ... See more keywords
Improved activity of SnO for the photocatalytic oxygen evolution
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Saudi Chemical Society"
DOI: 10.1016/j.jscs.2017.07.005
Abstract: Abstract SnO prepared by soft chemistry exhibits a black color and semiconducting properties. The X-ray diffraction indicates a tetragonal symmetry (SG: P4/nmm) with nano crystallites of an average size of 85 nm. The forbidden band, determined… read more here.
Keywords: oxygen evolution; improved activity; activity sno; sno ... See more keywords
Improved Activity of Rifampicin Against Biofilms of Staphylococcus aureus by Multicomponent Complexation
Sign Up to like & getrecommendations! Published in 2020 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-020-01706-z
Abstract: The aim of this study was to evaluate a multicomponent complex (MC) between rifampicin (RIF), β-cyclodextrin (β-CD), and selected amino acids to enhance the solubility and antibiofilm activity of RIF. After performing phase-solubility studies that… read more here.
Keywords: improved activity; rifampicin; staphylococcus aureus; biofilms staphylococcus ... See more keywords