Marfan syndrome: improved clinical history results in expanded natural history
Sign Up to like & getrecommendations! Published in 2018 at "Genetics in Medicine"
DOI: 10.1038/s41436-018-0399-4
Abstract: Life expectancy for a person with Marfan syndrome has essentially doubled over the past four decades. During this period, the clinical histories of the organs managed routinely have improved, and will continue to be. Prominent… read more here.
Keywords: marfan syndrome; history; syndrome improved; improved clinical ... See more keywords
Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion
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DOI: 10.1182/blood.2020007079
Abstract: Two case series examining the impact of convalescent plasma on patients with COVID-19 suggest some clinical benefit from early administration and modest impact on parameters of inflammation. Further assessment of the impact of this intervention… read more here.
Keywords: mortality among; plasma; clinical symptoms; improved clinical ... See more keywords
Association of immune-related adverse events (irAEs) with improved clinical outcome in sarcoma patients treated with immune checkpoint blockade (ICB).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.11510
Abstract: 11510Background: IrAEs are associated with improved clinical outcomes after treatment with ICB in select epithelial malignancies. We hypothesized that sarcoma patients (pts) treated with ICB who de... read more here.
Keywords: icb; immune related; improved clinical; related adverse ... See more keywords
Strategies to Uplift Novel Mendelian Gene Discovery for Improved Clinical Outcomes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.674295
Abstract: Rare genetic disorders, while individually rare, are collectively common. They represent some of the most severe disorders affecting patients worldwide with significant morbidity and mortality. Over the last decade, advances in genomic methods have significantly… read more here.
Keywords: clinical outcomes; improved clinical; novel mendelian; gene ... See more keywords