Aptamer-decorated polydiacetylene micelles with improved targeting of cancer cells.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.04.071
Abstract: In this study, a "click and hybridization" strategy was developed for the functionalization of polydiacetylene micelles with a targeting aptamer ligand. Decoration of the nanocarriers with an anti-Annexin A2 sequence efficiently triggered enhanced internalization of… read more here.
Keywords: improved targeting; micelles improved; decorated polydiacetylene; aptamer decorated ... See more keywords
Oncolytic Adenoviruses: Strategies for Improved Targeting and Specificity
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12061504
Abstract: Cancer is a major health problem. Most of the treatments exhibit systemic toxicity, as they are not targeted or specific to cancerous cells and tumors. Adenoviruses are very promising gene delivery vectors and have immense… read more here.
Keywords: improved targeting; adenoviruses strategies; specificity oncolytic; oncolytic adenoviruses ... See more keywords