Induction of Bleb Structures in Lipid Nanoparticle Formulations of mRNA Leads to Improved Transfection Potency.
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DOI: 10.1002/adma.202303370
Abstract: The transfection potency of lipid nanoparticle (LNP) mRNA systems is critically dependent on the ionizable cationic lipid component. LNP mRNA systems composed of optimized ionizable lipids often display distinctive mRNA rich "bleb" structures. Here we… read more here.
Keywords: improved transfection; transfection potency; potency; lipid nanoparticle ... See more keywords