Toward an Improved Understanding of Anhedonia.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA psychiatry"
DOI: 10.1001/jamapsychiatry.2018.4600
Abstract: Anhedonia, the reduced ability to experience pleasure, has been critically implicated in a wide range of adolescent mental disorders and suicidal behaviors.1,2 Presently, medication as well as most first-line psychotherapeutic approaches do not sufficiently address… read more here.
Keywords: research; understanding anhedonia; toward improved; improved understanding ... See more keywords
Progress toward improved understanding of antibody maturation.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2020.11.008
Abstract: Upon encountering an antigen, antibodies mature through various rounds of somatic mutations, resulting in higher affinities and specificities to the particular antigen. We review recent progress in four areas of antibody maturation studies. (1) Next-generation… read more here.
Keywords: antibody; improved understanding; progress toward; antibody maturation ... See more keywords
Improved Understanding of Material Behavior using Correlative In-situ Techniques
Sign Up to like & getrecommendations! Published in 2017 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927617004627
Abstract: In order to advance flexible electronic technologies it is important to study the combined electromechanical properties of thin metal films on polymers substrates under mechanical load. Ductile films and lines are an integral part of… read more here.
Keywords: ductile films; material behavior; improved understanding; material ... See more keywords
Deciphering Alzheimer’s disease: predicting new therapeutic strategies via improved understanding of biology and pathogenesis
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Therapeutic Targets"
DOI: 10.1080/14728222.2020.1790530
Abstract: ABSTRACT Introduction There is no cure for Alzheimer’s disease (AD). One explanation may pertain to the need to intervene as early as possible upstream from the accumulation of β-amyloid plaques and tau tangles. Areas covered… read more here.
Keywords: alzheimer disease; deciphering alzheimer; disease; therapeutic strategies ... See more keywords
CRISPR-Cas Biology and Its Application to Infectious Diseases
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01307-18
Abstract: Infectious diseases remain a global threat contributing to excess morbidity and death annually, with the persistent potential for destabilizing pandemics. Improved understanding of the pathogenesis of bacteria, viruses, fungi, and parasites, along with rapid diagnosis… read more here.
Keywords: infectious diseases; crispr cas; cas biology; improved understanding ... See more keywords
Eight Simple Guidelines for Improved Understanding of Transformations and Nonlinear Effects
Sign Up to like & getrecommendations! Published in 2021 at "Organizational Research Methods"
DOI: 10.1177/1094428121991907
Abstract: Transforming variables before analysis or applying a transformation as a part of a generalized linear model are common practices in organizational research. Several methodological articles addressi... read more here.
Keywords: understanding transformations; simple guidelines; improved understanding; transformations nonlinear ... See more keywords
Improved understanding of biorisk for research involving microbial modification using annotated sequences of concern
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1124100
Abstract: Regulation of research on microbes that cause disease in humans has historically been focused on taxonomic lists of ‘bad bugs’. However, given our increased knowledge of these pathogens through inexpensive genome sequencing, 5 decades of… read more here.
Keywords: concern; biorisk research; understanding biorisk; sequences concern ... See more keywords