Articles with "improves survival" as a keyword



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Haematological cancer: Lenalidomide improves survival after ASCT

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Published in 2017 at "Nature Reviews Clinical Oncology"

DOI: 10.1038/nrclinonc.2017.135

Abstract: The outcomes of a phase II, single-arm study involving patients with microsatellite-unstable (MSI) metastatic colorectal cancer receiving treatment with nivolumab reveal high levels of effectiveness. In a heavily pretreated population, 23 patients (31% of the… read more here.

Keywords: survival asct; improves survival; haematological cancer; cancer ... See more keywords

Sarcoma: Local hyperthermia improves survival

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Published in 2018 at "Nature Reviews Clinical Oncology"

DOI: 10.1038/nrclinonc.2018.38

Abstract: Patients with localized high-risk soft-tissue sarcoma (STS) often have disease relapse after local treatment. Neoadjuvant chemotherapy (NACT) improves the survival outcomes of these patients, although emerging data suggest that additional regional hyperthermia (RHT) can further… read more here.

Keywords: nact alone; hyperthermia; treatment; improves survival ... See more keywords
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VA-ECMO improves survival in cardiogenic shock

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Published in 2020 at "Nature Reviews Cardiology"

DOI: 10.1038/s41569-020-00450-y

Abstract: In the HAUSER randomized, placebo­ controlled clinical trial, paediatric patients (aged 10–17 years) with heterozygous familial hypercholesterolaemia treated with evolocumab (a fully human monoclonal antibody against PCSK9) for 24 weeks had a 44.5% mean reduction… read more here.

Keywords: reduction; group; improves survival; cardiogenic shock ... See more keywords
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Adjuvant nivolumab improves survival after radical cystectomy

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Published in 2021 at "Nature Reviews Urology"

DOI: 10.1038/s41585-021-00493-x

Abstract: A phase III randomized, controlled trial has investigated the role of adjuvant treatment in high-risk muscle-invasive urothelial carcinoma after radical surgery. Patients with muscleinvasive cancer who had undergone radical cystectomy received nivolumab (240 mg intravenously;… read more here.

Keywords: group; improves survival; adjuvant nivolumab; radical cystectomy ... See more keywords

An ALPHA7 Nicotinic Acetylcholine Receptor Agonist (GTS-21) Promotes C2C12 Myonuclear Accretion in Association with Release of Interleukin-6 (IL-6) and Improves Survival in Burned Mice

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Published in 2017 at "SHOCK"

DOI: 10.1097/shk.0000000000000849

Abstract: ABSTRACT The role of interleukin-6 (IL-6) in physiological processes and disease is poorly understood. The hypothesis tested in this study was that selective alpha7 acetylcholine receptor (&agr;7AChR) agonist, GTS-21, releases IL-6 in association with myonuclear… read more here.

Keywords: myonuclear accretion; improves survival; il6ko mice; mice ... See more keywords

Ascorbic acid 2‐glucoside improves survival, quality, and fertility of frozen‐thawed C57Bl/6J and C57Bl/6N mouse spermatozoa

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Published in 2024 at "Andrology"

DOI: 10.1111/andr.13768

Abstract: Ascorbic acid 2‐glucoside (AA2G) is a stabilized form of ascorbic acid and a potent antioxidant. Ascorbic acid is present in the testes and epididymis and helps maintain the physiological integrity of reproductive organs. Its properties… read more here.

Keywords: acid glucoside; survival quality; glucoside improves; ascorbic acid ... See more keywords

Neurally adjusted ventilatory assist improves survival, and its early application accelerates weaning in preterm infants

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Published in 2024 at "Pediatrics International"

DOI: 10.1111/ped.15831

Abstract: Evidence to show that neurally adjusted ventilatory assist (NAVA) improves clinical outcomes is lacking. We aimed to analyze whether NAVA improves respiratory outcomes in preterm infants who require invasive mechanical ventilation. read more here.

Keywords: assist improves; ventilatory assist; preterm infants; adjusted ventilatory ... See more keywords

Targeting aging cells improves survival

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Published in 2021 at "Science"

DOI: 10.1126/science.abi4474

Abstract: Drugs that remove senescent cells cut coronavirus deaths in old mice Older age is associated with increased COVID-19 severity and mortality (1). Whether this is due to preexisting age-related health conditions or aging per se… read more here.

Keywords: targeting aging; infection; cells improves; improves survival ... See more keywords

ZLN005 improves the survival of polymicrobial sepsis by increasing the bacterial killing via inducing lysosomal acidification and biogenesis in phagocytes

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1089905

Abstract: Polymicrobial sepsis still has a high mortality rate despite the development of antimicrobial agents, elaborate strategies to protect major organs, and the investment of numerous medical resources. Mitochondrial dysfunction, which acts as the center of… read more here.

Keywords: sepsis; zln005 improves; improves survival; sepsis increasing ... See more keywords