Improving efficacy of glycoconjugate vaccines: from chemical conjugates to next generation constructs.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2020.03.015
Abstract: Glycoconjugate vaccines are among the safest and most successful vaccines developed during the past 30 years. Since the first semisynthetic chemical conjugate vaccine licensed in the 1980's to protect human against Haemophilus influenzae type b… read more here.
Keywords: improving efficacy; efficacy glycoconjugate; chemical; glycoconjugate vaccines ... See more keywords
Improving efficacy of PD-1 blockade in unresponsive lymphoma tumors with in situ vaccination through induction of a highly efficient cross-presenting dendritic cell subset.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.5_suppl.76
Abstract: 76Background: Low-grade non-Hodgkin’s B-cell lymphomas are generally incurable; preliminary results with anti-PD-1 therapy have yielded low response rates. Tumoral DC infiltration correlates with efficacy of checkpoint blockade and tumor-targeted vaccines represent promising, novel treatment strategies… read more here.
Keywords: improving efficacy; blockade unresponsive; lymphoma tumors; efficacy blockade ... See more keywords