Articles with "improving experimental" as a keyword



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A simple, versatile and robust centrifugation‐based filtration protocol for the isolation and quantification of α‐synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α‐synuclein research

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Published in 2020 at "Journal of Neurochemistry"

DOI: 10.1111/jnc.14955

Abstract: Increasing evidence suggests that the process of alpha‐synuclein (α‐syn) aggregation from monomers into amyloid fibrils and Lewy bodies, via oligomeric intermediates plays an essential role in the pathogenesis of different synucleinopathies, including Parkinson's disease (PD),… read more here.

Keywords: experimental reproducibility; centrifugation based; syn; improving experimental ... See more keywords