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Improving NanoCluster Beacon performance by blocking the unlabeled NC probes.

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1 Published in 2019 at "Chemical communications"

DOI: 10.1039/c8cc08291j

Abstract: While NanoCluster Beacon (NCB) is a versatile molecular probe, it suffers from a low target-specific signal issue due to impurities. Here we show that adding a "blocker" strand to the reaction can effectively block the… read more here.

Keywords: performance blocking; improving nanocluster; blocking unlabeled; beacon ... See more keywords