Improving Top-Down Sequence Coverage with Targeted Fragment Matching
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DOI: 10.1021/jasms.4c00161
Abstract: Top-down mass spectrometry (TDMS) of intact proteins and antibodies enables direct determination of truncations, sequence variants, post-translational modifications, and disulfides without the need for any proteolytic cleavage. While mass deconvolution of top-down tandem mass spectra… read more here.
Keywords: improving top; sequence coverage; mass; sequence ... See more keywords