Synthesis and organic impurity profiling of 4-methoxymethamphetamine hydrochloride and its precursors.
Sign Up to like & getrecommendations! Published in 2017 at "Forensic science international"
DOI: 10.1016/j.forsciint.2016.11.041
Abstract: 4-Methoxymethamphetamine (PMMA) was synthesised from star anise and from 4-methoxytoluene and the organic impurity profiles examined. These two starting materials are unrestricted chemicals in many jurisdictions and contain the requisite functional groups and are thus… read more here.
Keywords: organic impurity; methoxymethamphetamine hydrochloride; impurity profiling; synthesis organic ... See more keywords
Green HPTLC-densitometric approach for simultaneous determination and impurity- profiling of ebastine and phenylephrine hydrochloride
Sign Up to like & getrecommendations! Published in 2019 at "Microchemical Journal"
DOI: 10.1016/j.microc.2019.04.043
Abstract: Abstract Although analytical HPLC-technique can be considered as a well-accepted versatile approach for the drugs' separation, quantification, as well as impurity profiling, its regular adoption shows increasing environmental concerns provoked by high energy-consumption, instrument and… read more here.
Keywords: hptlc; phenylephrine hydrochloride; approach; impurity profiling ... See more keywords
Development of Impurity Profiling Methods Using Modern Analytical Techniques
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DOI: 10.1080/10408347.2016.1169913
Abstract: ABSTRACT This review gives a brief introduction about the process- and product-related impurities and emphasizes on the development of novel analytical methods for their determination. It describes the application of modern analytical techniques, particularly the… read more here.
Keywords: development impurity; development; modern analytical; impurity profiling ... See more keywords
Quinquennial Review of Progress in Degradation Studies and Impurity Profiling: An Instrumental Perspective Statistics
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DOI: 10.1080/10408347.2019.1615863
Abstract: Abstract Degradation studies of drug give insightful information about the intrinsic stability of the molecule, the possible degradents formed during shelf life and thus, aid in the subsequent development of its stable formulation. For identification… read more here.
Keywords: degradation; quinquennial review; review progress; degradation studies ... See more keywords
Impurity profiling of amphetamine and methamphetamine using Gas Chromatography Mass Spectrometry (GCMS) harmonised methods
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DOI: 10.17576/jsm-2017-4601-19
Abstract: Impurity profiling of drug seizures is a scientific approach employed to understand drug trafficking networks thus has becoming increasingly important in criminal investigation. This paper presents the feasibility of using the Collaborative Harmonisation of Methods… read more here.
Keywords: gas chromatography; methamphetamine; profiling amphetamine; amphetamine methamphetamine ... See more keywords
Analytical Performance and Greenness Evaluation of Five Multi-Level Design Models Utilized for Impurity Profiling of Favipiravir, a Promising COVID-19 Antiviral Drug
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27123658
Abstract: In 2018, the discovery of carcinogenic nitrosamine process related impurities (PRIs) in a group of widely used drugs led to the recall and complete withdrawal of several medications that were consumed for a long time,… read more here.
Keywords: impurity profiling; level design; multi level; level ... See more keywords